AMPD3 Rabbit pAb (APR20053N)

CAT: 0882-APR20053N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APR20053N-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

This gene encodes a member of the AMP deaminase gene family. The encoded protein is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. This gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. Mutations in this gene lead to the clinically asymptomatic, autosomal recessive condition erythrocyte AMP deaminase deficiency. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality AMPD3 Rabbit pAb (APR20053N) .

Synonyms

AMPD3

Gene ID

272

UniProt

Q01432

Dilution

IF 1:50 - 1:200

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 24kDa/71kDa/76kDa/88kDa/89kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=272

Uniprot URL

https://www.uniprot.org/uniprot/Q01432

AA Sequence

MALSSEPAEMPRQFPKLNISEVDEQVRLLAEKVFAKVLREEDSKDALSLFTVPEDCPIGQKEAKERELQKELAEQKSVETAKRKKSFKMIRSQSLSLQMPPQQDWKGPPAASPAMSPTTPVVTGATSLPTPAPYAMPEFQRVTISGDYCAGITLEDYEQAAKSLAKALMIREKYARLAYHRFPRITSQYLGHPRADTAPPEEGLPDFHPPPLPQEDPYCLDDAPPNLDYLVHMQGGILFVYDNKKMLEHQEPHSLPYPDL

UniProtKB · Q01432

AMP deaminase 3

AMPD3_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q01432
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: AMPD3
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: 3.5.4.6
Processing: —
Secondary accessions: A0AUX0, B7Z2S2, B7Z763, B7Z877

Protein keywords

Coding sequence diversity

Alternative splicing

Disease

Disease variant

Molecular function

Hydrolase

Ligand

Metal-bindingZinc

Biological process

Nucleotide metabolism

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome

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