MAPK12 Rabbit pAb (APR19641N)

CAT: 0882-APR19641N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APR19641N-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

Activation of members of the mitogen-activated protein kinase family is a major mechanism for transduction of extracellular signals. Stress-activated protein kinases are one subclass of MAP kinases. The protein encoded by this gene functions as a signal transducer during differentiation of myoblasts to myotubes.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MAPK12 Rabbit pAb (APR19641N) .

Synonyms

MAPK12; ERK-6; ERK3; ERK6; MAPK 12; P38GAMMA; PRKM12; SAPK-3; SAPK3

Gene ID

6300

UniProt

P53778

Cellular Locus

Cytoplasm, Mitochondrion, Nucleus

Dilution

WB 1:2000 - 1:5000 IHC 1:50 - 1:200

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 40kDa/41kDa Observed MW: 42kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6300

Uniprot URL

https://www.uniprot.org/uniprot/P53778

AA Sequence

EFVQRLQSDEAKNYMKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAEQRVTAGEALAHPYFESLHDTEDEPQVQKYDDSFDDVDRTLDEWKRVTYKEVLSFKPPRQLGARVSKETPL

UniProtKB · P53778

Mitogen-activated protein kinase 12

MK12_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P53778
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: MAPK12
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: MAP kinase 12, MAPK 12
EC number: 2.7.11.24
Processing: —
Secondary accessions: Q14260, Q6IC53, Q99588, Q99672

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingMagnesiumMetal-bindingNucleotide-binding

Biological process

Cell cycleStress responseTranscriptionTranscription regulation

Cellular component

CytoplasmMitochondrionNucleus

Molecular function

KinaseSerine/threonine-protein kinaseTransferase

PTM

PhosphoproteinUbl conjugation

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