P2RX3 Rabbit pAb (APR19580N)

CAT: 0882-APR19580N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APR19580N-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality P2RX3 Rabbit pAb (APR19580N) .

Synonyms

P2RX3; P2X3

Gene ID

5024

UniProt

P56373

Cellular Locus

Membrane, Multi-pass membrane protein

Dilution

WB 1:500 - 1:2000

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 44kDa Observed MW: 44kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5024

Uniprot URL

https://www.uniprot.org/uniprot/P56373

AA Sequence

AFTSVGVGTVLCDIILLNFLKGADQYKAKKFEEVNETTLKIAALTNPVYPSDQTTAEKQSTDSGAFSIGH

UniProtKB · P56373

P2X purinoceptor 3

P2RX3_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P56373
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: P2RX3
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: P2X3
EC number: —
Processing: —
Secondary accessions: Q6DK37, Q9UQB6

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Ligand

ATP-bindingCalciumMagnesiumMetal-bindingNucleotide-binding

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoprotein

Molecular function

Ion channelLigand-gated ion channelReceptor

Biological process

Ion transportTransport

Domain

TransmembraneTransmembrane helix

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Alternative Products

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E45R19580N-100	P2RX3 Rabbit pAb
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