MOGS Rabbit pAb (APR19347N)

CAT: 0882-APR19347N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APR19347N-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

This gene encodes the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc (3) -Man (9) -GlcNAc (2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum. Defects in this gene are a cause of type IIb congenital disorder of glycosylation (CDGIIb) . Two transcript variants encoding different isoforms have been found for this gene.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MOGS Rabbit pAb (APR19347N) .

Synonyms

MOGS; CDG2B; CWH41; DER7; GCS1

Gene ID

7841

UniProt

Q13724

Cellular Locus

Endoplasmic reticulum membrane, Single-pass type II membrane protein

Dilution

WB 1:500 - 1:2000

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 80kDa/91kDa Observed MW: 80kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7841

Uniprot URL

https://www.uniprot.org/uniprot/Q13724

AA Sequence

RWVLAWYRARRAVTLHSAPPVLPADSSSPAVAPDLFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGTTPGTPKLRHTCEQGDGVGPYGWEFHDGLSFGRQHIQDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQDSGTSALPLVSLFFYVVTDGKEVLLPEVGAKGQLKFISGHTSELGDFRFTLLPPTSPGDTAPKYGSYNVFWTSNPGLPLLTEMVKSRLNSWFQHRPPGAPPERYLGLPGSLKWEDRGPSGQGQGQFL

UniProtKB · Q13724

Mannosyl-oligosaccharide glucosidase

MOGS_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q13724
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: MOGS
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: 3.2.1.106
Processing: —
Secondary accessions: A8K938, F5H6D0, Q17RN9, Q8TCT5

Protein keywords

Coding sequence diversity

Alternative splicing

Disease

Disease variant

Cellular component

Endoplasmic reticulumMembrane

PTM

Glycoprotein

Molecular function

GlycosidaseHydrolase

Technical term

Proteomics identificationReference proteome

Domain

Signal-anchorTransmembraneTransmembrane helix

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