CDCA8 Rabbit pAb (APR19223N)

CAT: 0882-APR19223N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APR19223N-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

This gene encodes a component of the chromosomal passenger complex. This complex is an essential regulator of mitosis and cell division. This protein is cell-cycle regulated and is required for chromatin-induced microtubule stabilization and spindle formation. Alternate splicing results in multiple transcript variants. Pseudgenes of this gene are found on chromosomes 7, 8 and 16.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CDCA8 Rabbit pAb (APR19223N) .

Synonyms

CDCA8; BOR; BOREALIN; DasraB; MESRGP; borealin

Gene ID

55143

UniProt

Q53HL2

Cellular Locus

Chromosome, Cytoplasm, Nucleus, centromere, cytoskeleton, nucleolus, spindle

Dilution

WB 1:500 - 1:1000 IHC 1:50 - 1:100

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 31kDa Observed MW: 36-38kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=55143

Uniprot URL

https://www.uniprot.org/uniprot/Q53HL2

AA Sequence

MAPRKGSSRVAKTNSLRRRKLASFLKDFDREVEIRIKQIESDRQNLLKEVDNLYNIEILRLPKALREMNWLDYFALGGNKQALEEAATADLDITEINKLTAEAIQTPLKSAKTRKVIQVDEMIVEEEEEEENERKNLQTARVKRCPPSKKRTQSIQGKGKGKRSSRANTVTPAVGRLEVSMVKPTPGLTPRFDSRVFKTPGLRTPAAGERIYNISGNGSPLADSKEIFLTVPVGGGESLRLLASDLQRHSIAQLDPEALGNIKKLSNRLAQICSSIRTHK

UniProtKB · Q53HL2

Borealin

BOREA_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q53HL2
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: CDCA8
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: —
Processing: —
Secondary accessions: D3DPT4, Q53HN1, Q96AM3, Q9NVW5

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Biological process

Cell cycleCell divisionMitosis

Cellular component

CentromereChromosomeCytoplasmCytoskeletonNucleus

PTM

Isopeptide bondPhosphoproteinUbl conjugation

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