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RTCB Rabbit pAb (APR17929N)

CAT: 0882-APR17929N-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0882-APR17929N-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RTCB Rabbit pAb (APR17929N) .
Synonyms
RTCB; C22orf28; DJ149A16.6; FAAP; HSPC117
Gene ID
51493
UniProt
Q9Y3I0
Cellular Locus
Cytoplasm, Nucleus
Dilution
WB 1:500 - 1:2000
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 55kDa Observed MW: 55kDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=51493
Uniprot URL
https://www.uniprot.org/uniprot/Q9Y3I0
AA Sequence
EIFNEYAAKKMGIDHKGQVCVMIHSGSRGLGHQVATDALVAMEKAMKRDKIIVNDRQLACARIASPEGQDYLKGMAAAGNYAWVNRSSMTFLTRQAFAKVFNTTPDDLDLHVIYDVSHNIAKVEQHVVDGKERTLLVHRKGSTRAFPPHHPLIAVDYQLTGQPVLIGGTMGTCSYVLTGTEQGMTETFGTTCHGAGRALSRAKSRRNLDFQDVLDKLADMGIAIRVASPKLVMEEAPESYKNVTDVVNTCHDAGISKKAIKLRPIAVIKG

UniProtKB · Q9Y3I0

RNA-splicing ligase RTCB

RTCB_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9Y3I0
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
RTCB
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
6.5.1.8
Processing
—
Secondary accessions
B2R6A8, Q6IAI0, Q9BWL4, Q9NTH1, Q9P037, Q9P0J3
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Cellular component

CytoplasmNucleus

Ligand

GTP-bindingManganeseMetal-bindingNucleotide-binding

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Molecular function

Ligase

Biological process

tRNA processing