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GRIN2D Rabbit pAb (APR17717N)

CAT: 0882-APR17717N-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0882-APR17717N-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D) .
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GRIN2D Rabbit pAb (APR17717N) .
Synonyms
GRIN2D; EB11; EIEE46; GluN2D; NMDAR2D; NR2D; NMDA 2D
Gene ID
2906
UniProt
O15399
Cellular Locus
Cell junction, Cell membrane, Multi-pass membrane protein, postsynaptic cell membrane, synapse
Applications
WB (Mus musculus, Rattus norvegicus)
Dilution
WB 1:500 - 1:2000
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 143kDa Observed MW: 170kDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2906
Uniprot URL
https://www.uniprot.org/uniprot/O15399
AA Sequence
GAQALLRDYGFLPELGHDCRAQNRTHRGESLHRYFMNITWDNRDYSFNEDGFLVNPSLVVISLTRDRTWEVVGSWEQQTLRLKYPLWSRYGRFLQPVDDTQHLTVATLEERPFVIVEPADPISGTCIRDSVPCRSQLNRTHSPPPDAPRPE

UniProtKB · O15399

Glutamate receptor ionotropic, NMDA 2D

NMDE4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O15399
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GRIN2D
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
GluN2D
EC number
—
Processing
Precursor
Secondary accessions
—
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Ligand

CalciumMagnesium

Cellular component

Cell membraneMembranePostsynaptic cell membraneSynapse

Disease

Disease variantEpilepsy

PTM

Disulfide bondGlycoproteinMethylationPhosphoprotein

Molecular function

Ion channelLigand-gated ion channelReceptor

Biological process

Ion transportTransport

Domain

SignalTransmembraneTransmembrane helix

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