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PCDH19 Rabbit pAb (APR17702N)

CAT: 0882-APR17702N-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0882-APR17702N-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the delta-2 protocadherin subclass of the cadherin superfamily. The encoded protein is thought to be a calcium-dependent cell-adhesion protein that is primarily expressed in the brain. Defects in this gene are a cause of epilepsy female-restricted with mental retardation (EFMR) . Three transcript variants encoding different isoforms have been found for this gene.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PCDH19 Rabbit pAb (APR17702N) .
Synonyms
PCDH19; EFMR; EIEE9
Gene ID
57526
UniProt
Q8TAB3
Cellular Locus
Cell membrane, Single-pass type I membrane protein
Applications
WB (Mus musculus) IF (Mus musculus)
Dilution
WB 1:500 - 1:2000
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 121kDa/126kDa Observed MW: 170kDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=57526
Uniprot URL
https://www.uniprot.org/uniprot/Q8TAB3
AA Sequence
LINGTAEVYIPRNSGIGYLVTVVKAEDYDEGENGRVTYDMTEGDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASALVLIYLSPALDAQESMGSVNLS

UniProtKB · Q8TAB3

Protocadherin-19

PCD19_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8TAB3
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PCDH19
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B0LDS4, E9PAM6, Q5JTG1, Q5JTG2, Q68DT7, Q9P2N3
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

CalciumMetal-binding

Biological process

Cell adhesion

Cellular component

Cell membraneMembrane

Disease

Disease variantEpilepsyIntellectual disability

PTM

Disulfide bondGlycoprotein

Domain

RepeatSignalTransmembraneTransmembrane helix

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