S100B Rabbit pAb (APR17508N)

CAT: 0882-APR17508N-01Size: 50 µLDry Ice: NoHazardous: No

1 / 1

CAT#:0882-APR17508N-01Size:50 µL

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Background

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality S100B Rabbit pAb (APR17508N) .

Synonyms

NEF; S100; S100-B; S100beta; S100B; S100 beta

Gene ID

6285

UniProt

P04271

Cellular Locus

Cytoplasm, Nucleus

Applications

WB (Homo sapiens, Mus musculus)

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 IP 1:50 - 1:200

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 10kDa Observed MW: 11KDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6285

Uniprot URL

https://www.uniprot.org/uniprot/P04271

AA Sequence

MSELEKAMVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDNDGDGECDFQEFMAFVAMVTTACHEFFEHE

UniProtKB · P04271

Protein S100-B

S100B_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P04271
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: S100B
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: —
Processing: —
Secondary accessions: D3DSN6

Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

Acetylation

Ligand

CalciumMetal-bindingZinc

Biological process

Cell adhesion

Cellular component

CytoplasmNucleusSecreted

Domain

Repeat

Related Products

Catalog	Name
APR19508N-01	PALD1 Rabbit pAb (APR19508N)
APR17908N-01	CPSF4 Rabbit pAb (APR17908N)
APR17708N-01	SCN3A Rabbit pAb (APR17708N)
APR17501N-01	TNFRSF6B Rabbit pAb (APR17501N)
APR17308N-01	SPHK1 Rabbit pAb (APR17308N)
APR27508N-01	UGT2B10 Rabbit pAb (APR27508N)
APR18508N-01	MPST Rabbit pAb (APR18508N)
APR17808N-01	MAP3K13 Rabbit pAb (APR17808N)
APR17598N-01	PPP3R1 Rabbit pAb (APR17598N)
APR17548N-01	STAT6 Rabbit pAb (APR17548N)

Alternative Products

Catalog	Name
NBP2-53188-20ug	Rabbit Monoclonal S100B Antibody (S100B/1706R)
HY-P80891-01	S100B Antibody (Rabbit)
MBS8554412-01	S100B Rabbit pAb
MBS4761923-01	S100B Rabbit mAb