[KO Validated] CDK2 Rabbit pAb (APR17405N)

• Background:

  This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B) . Alternative splicing results in multiple transcript variants.

• Synonyms:

  CDK2; CDKN2; p33 (CDK2)

• Gene ID:

  1017

• UniProt:

  P24941

• Cellular Locus:

  Cajal body, Cytoplasm, Endosome, Nucleus, centrosome, cytoskeleton, microtubule organizing center

• Applications:

  IHC (Human colon cancer cell, Mouse kidney) WB (Human colon cancer cell, Mouse kidney, Mus musculus, Homo sapiens, Rattus norvegicus)

• Dilution:

  WB 1:500 - 1:2000 IHC 1:50 - 1:100 IP 1:50 - 1:200

• Form:

  Liquid

• Buffer:

  Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Molecular Weight:

  Calculated MW: 30kDa/33kDa Observed MW: 34KDa

• Storage Conditions:

  Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality [KO Validated] CDK2 Rabbit pAb (APR17405N) .

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1017

• Uniprot URL:

  https://www.uniprot.org/uniprot/P24941

• AA Sequence:

  Email for sequence