PKR/EIF2AK2 Rabbit mAb (AMR12759N)

• Background:

  The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

• Synonyms:

  EIF2AK1; PKR; PPP1R83; PRKR; Eif2ak2; EIF2AK2

• Gene ID:

  5610

• UniProt:

  P19525

• Cellular Locus:

  Cytoplasm, Nucleus, perinuclear region

• Dilution:

  WB 1:500 - 1:2000

• Form:

  Liquid

• Buffer:

  Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.

• Molecular Weight:

  Calculated MW: 68kDa Observed MW: 70KDa

• Storage Conditions:

  Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PKR/EIF2AK2 Rabbit mAb (APR24494N5) .

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5610

• Uniprot URL:

  https://www.uniprot.org/uniprot/P19525

• AA Sequence:

  Email for sequence