COX6B1 Rabbit mAb (AMR11525N)

CAT: 0882-AMR11525N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-AMR11525N-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIb. Mutations in this gene are associated with severe infantile encephalomyopathy. Three pseudogenes COX6BP-1, COX6BP-2 and COX6BP-3 have been found on chromosomes 7, 17 and 22q13.1-13.2, respectively.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality COX6B1 Rabbit mAb (AMR11525N) .

Synonyms

COX6B1; COX6B; COXG; COXVIb1; cytochrome c oxidase subunit 6B1

Gene ID

1340

UniProt

P14854

Cellular Locus

Mitochondrion intermembrane space

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 10kDa Observed MW: 10KDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1340

Uniprot URL

https://www.uniprot.org/uniprot/P14854

AA Sequence

Email for sequence

UniProtKB · P14854

Cytochrome c oxidase subunit 6B1

CX6B1_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P14854
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: COX6B1
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: —
Processing: —
Secondary accessions: B2R5C9, Q6IBL4

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationDisulfide bond

Disease

Disease variantPrimary mitochondrial disease

Cellular component

MembraneMitochondrionMitochondrion inner membrane

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