KAT13A / SRC1 Rabbit mAb (AMR11461N)

CAT: 0882-AMR11461N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-AMR11461N-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KAT13A / SRC1 Rabbit mAb (AMR11461N) .

Synonyms

F-SRC-1; KAT13A; RIP160; SRC1; bHLHe42; bHLHe74

Gene ID

8648

UniProt

Q15788

Dilution

WB 1:500 - 1:2000 IP 1:50 - 1:200

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 157kDa Observed MW: 180KDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=8648

Uniprot URL

https://www.uniprot.org/uniprot/Q15788

AA Sequence

Email for sequence

UniProtKB · Q15788

Nuclear receptor coactivator 1

NCOA1_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q15788
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: NCOA1
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: NCoA-1
EC number: 2.3.1.48
Processing: —
Secondary accessions: O00150, O43792, O43793, Q13071, Q13420, Q2T9G5, Q53SX3, Q6GVI5, Q7KYV3

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondMethylationPhosphoproteinUbl conjugation

Molecular function

ActivatorAcyltransferaseTransferase

Coding sequence diversity

Alternative splicingChromosomal rearrangement

Cellular component

Nucleus

Disease

Proto-oncogene

Domain

Repeat

Biological process

TranscriptionTranscription regulation

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