Phospho-IRF3-S396 Rabbit pAb (AMR01032N)

• Background:

  This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

• Synonyms:

  IIAE7; IRF3

• Gene ID:

  3661

• UniProt:

  Q14653

• Cellular Locus:

  Cytoplasm, Nucleus

• Applications:

  WB (Sus scrofa, Homo sapiens, Mus musculus)

• Dilution:

  WB 1:500 - 1:2000

• Form:

  Liquid

• Buffer:

  Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Molecular Weight:

  Calculated MW: 12kDa/16kDa/33kDa/47kDa/49kDa Observed MW: 45kDa

• Storage Conditions:

  Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-IRF3-S396 Rabbit pAb (AMR01032N) .

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3661

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q14653

• AA Sequence:

  Email for sequence