Phospho-IκBα-S32/36 Rabbit pAb (AMR01028N)

• Background:

  This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.

• Synonyms:

  IKBA; MAD-3; NFKBI; IKB alpha; NFKBIA; EDAID2

• Gene ID:

  4792

• UniProt:

  P25963

• Cellular Locus:

  Cytoplasm, Nucleus

• Applications:

  WB (Homo sapiens, Mus musculus, Mus musculus, Homo sapiens, Rattus norvegicus, Schisandra chinensis, Melodinus cochinchinensis, Gallus gallus, Cavia porcellus)

• Dilution:

  WB 1:500 - 1:1000

• Form:

  Liquid

• Buffer:

  Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Molecular Weight:

  Calculated MW: 35kDa Observed MW: 36kDa

• Storage Conditions:

  Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-IκBα-S32/36 Rabbit pAb (AMR01028N) .

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=4792

• Uniprot URL:

  https://www.uniprot.org/uniprot/P25963

• AA Sequence:

  SGLDS