RBFOX1 Mouse Monoclonal Antibody [Clone ID: LBI2C12]

• Background:

  The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U) GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2) . Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

• Synonyms:

  2BP1; A2BP1; FOX-1; FOX1; HRNBP1

• Gene Name:

  Homo sapiens RNA binding fox-1 homolog 1 (RBFOX1), transcript variant 4, mRNA.

• Gene ID:

  54715

• UniProt:

  Q9NWB1

• Conjugation:

  Unconjugated

• Dilution:

  WB 1:2000, IHC 1:150

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  RBFOX1

• Overview:

  Carrier-free (BSA/glycerol-free) RBFOX1 mouse monoclonal antibody, clone LBI2C12

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=54715

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9NWB1