NDUFS2 Mouse Monoclonal Antibody [Clone ID: LBI1D5]

• Background:

  The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I) . Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

• Synonyms:

  CI-49

• Gene Name:

  Homo sapiens NADH:ubiquinone oxidoreductase core subunit S2 (NDUFS2), transcript variant 1, mRNA; nuclear gene for mitochondrial product.

• Gene ID:

  4720

• UniProt:

  O75306

• Conjugation:

  Unconjugated

• Related Pathways:

  Alzheimer's disease, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease

• Field of Research:

  Alzheimer's disease, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease

• Dilution:

  WB 1:2000, IHC 1:150

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  NDUFS2

• Overview:

  Carrier-free (BSA/glycerol-free) NDUFS2 mouse monoclonal antibody, clone LBI1D5

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=4720

• Uniprot URL:

  https://www.uniprot.org/uniprot/O75306