CD30 (TNFRSF8) Mouse Monoclonal Antibody [Clone ID: LBI16H5]

• Background:

  The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

• Synonyms:

  CD30; D1S166E; Ki-1

• Gene Name:

  Homo sapiens TNF receptor superfamily member 8 (TNFRSF8), transcript variant 1, mRNA.

• Gene ID:

  943

• UniProt:

  P28908

• Conjugation:

  Unconjugated

• Related Pathways:

  Cytokine-cytokine receptor interaction

• Field of Research:

  Cytokine-cytokine receptor interaction

• Dilution:

  WB 1:2000, IHC 1:150, FLOW 1:100

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Function:

  Druggable Genome, ES Cell Differentiation/IPS, Stem cell - Pluripotency, Transmembrane

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  TNFRSF8

• Overview:

  Carrier-free (BSA/glycerol-free) TNFRSF8 mouse monoclonal antibody, clone LBI16H5

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=943

• Uniprot URL:

  https://www.uniprot.org/uniprot/P28908