Cullin 4B (CUL4B) Mouse Monoclonal Antibody [Clone ID: LBI1C4]

• Background:

  This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Synonyms:

  CUL-4B; MRXHF2; MRXS15; MRXSC; SFM2

• Gene Name:

  Homo sapiens cullin 4B (CUL4B), transcript variant 1, mRNA.

• Gene ID:

  8450

• UniProt:

  Q13620

• Conjugation:

  Unconjugated

• Related Pathways:

  Nucleotide excision repair, Ubiquitin mediated proteolysis

• Field of Research:

  Nucleotide excision repair, Ubiquitin mediated proteolysis

• Dilution:

  WB 1:2000, IHC 1:100

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  CUL4B

• Overview:

  Carrier-free (BSA/glycerol-free) CUL4B mouse monoclonal antibody, clone LBI1C4

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=8450

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q13620