Epoxide hydrolase (EPHX1) Mouse Monoclonal Antibody [Clone ID: LBI2C1]

• Background:

  Epoxide hydrolase is a critical biotransformation enzyme that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from the body. Epoxide hydrolase functions in both the activation and detoxification of epoxides. Mutations in this gene cause preeclampsia, epoxide hydrolase deficiency or increased epoxide hydrolase activity. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

• Synonyms:

  EPHX; EPOX; HYL1; MEH

• Gene Name:

  Homo sapiens epoxide hydrolase 1 (EPHX1), transcript variant 1, mRNA.

• Gene ID:

  2052

• UniProt:

  P07099

• Conjugation:

  Unconjugated

• Related Pathways:

  Metabolism of xenobiotics by cytochrome P450

• Field of Research:

  Metabolism of xenobiotics by cytochrome P450

• Dilution:

  WB 1:2000, FLOW 1:100

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Function:

  Druggable Genome, Protease

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  EPHX1

• Overview:

  Carrier-free (BSA/glycerol-free) EPHX1 mouse monoclonal antibody, clone LBI2C1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=2052

• Uniprot URL:

  https://www.uniprot.org/uniprot/P07099