Proteasome subunit alpha type 6 (PSMA6) Mouse Monoclonal Antibody [Clone ID: LBI7C2]

• Background:

  The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome. [provided by RefSeq]

• Synonyms:

  IOTA; p27K; PROS27

• Gene Name:

  Homo sapiens proteasome 20S subunit alpha 6 (PSMA6), transcript variant 1, mRNA.

• Gene ID:

  5687

• UniProt:

  P60900

• Conjugation:

  Unconjugated

• Related Pathways:

  Proteasome

• Field of Research:

  Proteasome

• Dilution:

  WB 1:500~2000, IHC 1:150, FLOW 1:100

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Function:

  Druggable Genome, Protease, Stem cell - Pluripotency

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  PSMA6

• Overview:

  Carrier-free (BSA/glycerol-free) PSMA6 mouse monoclonal antibody, clone LBI7C2

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=5687

• Uniprot URL:

  https://www.uniprot.org/uniprot/P60900