Fibrinogen gamma chain (FGG) Mouse Monoclonal Antibody [Clone ID: LBI1D1]

• Background:

  The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul

• Synonyms:

  Fibrinogen; fibrinogen gamma chain; gamma chain; gamma polypeptide

• Gene Name:

  Homo sapiens fibrinogen gamma chain (FGG), transcript variant gamma, mRNA.

• Gene ID:

  2266

• UniProt:

  P02679

• Conjugation:

  Unconjugated

• Related Pathways:

  Complement and coagulation cascades

• Field of Research:

  Complement and coagulation cascades

• Dilution:

  WB 1:400~4000, IHC 1:150

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Function:

  Druggable Genome, Secreted Protein, Transmembrane

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  FGG

• Overview:

  Carrier-free (glycerol/BSA-free) FGG mouse monoclonal antibody, clone LBI1D1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=2266

• Uniprot URL:

  https://www.uniprot.org/uniprot/P02679