CD163 Mouse Monoclonal Antibody [Clone ID: LBI1H1]

• Background:

  The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]

• Synonyms:

  M130; MM130; SCARI1

• Gene Name:

  Homo sapiens CD163 molecule (CD163), transcript variant 1, mRNA.

• Gene ID:

  9332

• UniProt:

  Q86VB7

• Conjugation:

  Unconjugated

• Dilution:

  WB 1:2000, IHC 1:150, IF 1:100

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Function:

  Druggable Genome, Secreted Protein, Transmembrane

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  CD163

• Overview:

  Carrier-free (BSA/glycerol-free) CD163 mouse monoclonal antibody, clone LBI1H1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=9332

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q86VB7