PDGF Receptor beta (PDGFRB) Mouse Monoclonal Antibody [Clone ID: LBI1D1]

• Background:

  This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Jul 2008]

• Synonyms:

  CD140B; IBGC4; IMF1; JTK12; PDGFR; PDGFR-1; PDGFR1

• Gene Name:

  Homo sapiens platelet derived growth factor receptor beta (PDGFRB), transcript variant 1, mRNA.

• Gene ID:

  5159

• UniProt:

  P09619

• Conjugation:

  Unconjugated

• Related Pathways:

  Calcium signaling pathway, Colorectal cancer, Cytokine-cytokine receptor interaction, Focal adhesion, Gap junction, Glioma, MAPK signaling pathway, Melanoma, Pathways in cancer, Prostate cancer, Regulation of actin cytoskeleton

• Field of Research:

  Calcium signaling pathway, Colorectal cancer, Cytokine-cytokine receptor interaction, Focal adhesion, Gap junction, Glioma, MAPK signaling pathway, Melanoma, Pathways in cancer, Prostate cancer, Regulation of actin cytoskeleton

• Dilution:

  WB 1:1000, IF 1:100

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Function:

  Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase, Transmembrane

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  PDGFRB

• Overview:

  Carrier-free (BSA/glycerol-free) PDGFRB mouse monoclonal antibody, clone LBI1D1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=5159

• Uniprot URL:

  https://www.uniprot.org/uniprot/P09619