Cytochrome C Oxidase subunit VIc (COX6C) Mouse Monoclonal Antibody [Clone ID: LBI4A5]

• Background:

  Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse subunit VIc. This gene is up-regulated in prostate cancer cells. A pseudogene has been found on chromosomes 16p12. [provided by RefSeq, Jul

• Synonyms:

  Cytochrome c oxidase subunit VIc; cytochrome c oxidase subunit VIc preprotein

• Gene Name:

  Homo sapiens cytochrome c oxidase subunit 6C (COX6C), mRNA.

• Gene ID:

  1345

• UniProt:

  P09669

• Conjugation:

  Unconjugated

• Related Pathways:

  Alzheimer's disease, Cardiac muscle contraction, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease

• Field of Research:

  Alzheimer's disease, Cardiac muscle contraction, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease

• Dilution:

  WB 1:4000, IHC 1:150, IF 1:100

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Function:

  Transmembrane

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  COX6C

• Overview:

  Carrier-free (BSA/glycerol-free) COX6C mouse monoclonal antibody, clone LBI4A5

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=1345

• Uniprot URL:

  https://www.uniprot.org/uniprot/P09669