Cbl c (CBLC) Mouse Monoclonal Antibody [Clone ID: LBI3D9]

• Background:

  This gene encodes a member of the Cbl family of E3 ubiquitin ligases. Cbl proteins play important roles in cell signaling through the ubiquitination and subsequent downregulation of tyrosine kinases. Expression of this gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]

• Synonyms:

  CBL-3; CBL-SL; RNF57

• Gene Name:

  Homo sapiens Cbl proto-oncogene C (CBLC), transcript variant 1, mRNA.

• Gene ID:

  23624

• UniProt:

  Q9ULV8

• Conjugation:

  Unconjugated

• Related Pathways:

  Chronic myeloid leukemia, Endocytosis, ErbB signaling pathway, Insulin signaling pathway, Jak-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Ubiquitin mediated proteolysis

• Field of Research:

  Chronic myeloid leukemia, Endocytosis, ErbB signaling pathway, Insulin signaling pathway, Jak-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Ubiquitin mediated proteolysis

• Dilution:

  WB 1:2000

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Function:

  Druggable Genome

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  CBLC

• Overview:

  Carrier-free (BSA/glycerol-free) CBLC mouse monoclonal antibody, clone LBI3D9

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=23624

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9ULV8