UBC6e (UBE2J1) Mouse Monoclonal Antibody [Clone ID: LBI1H10]

• Background:

  The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum (ER) and may contribute to quality control ER-associated degradation by the ubiquitin-proteasome system. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.

• Synonyms:

  CGI-76; HSPC153; HSPC205; HSU93243; NCUBE-1; NCUBE1; UBC6; UBC6E; Ubc6p

• Gene Name:

  Homo sapiens ubiquitin conjugating enzyme E2 J1 (UBE2J1), mRNA.

• Gene ID:

  51465

• UniProt:

  Q9Y385

• Conjugation:

  Unconjugated

• Related Pathways:

  Parkinson's disease, Ubiquitin mediated proteolysis

• Field of Research:

  Parkinson's disease, Ubiquitin mediated proteolysis

• Dilution:

  WB 1:2000

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Function:

  Transmembrane

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  UBE2J1

• Overview:

  Carrier-free (BSA/glycerol-free) UBE2J1 mouse monoclonal antibody, clone LBI1H10

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=51465

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9Y385