BAIAP2 Mouse Monoclonal Antibody [Clone ID: LBI8G8]

• Background:

  The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1) -binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

• Synonyms:

  BAP2; FLAF3; IRSP53

• Gene Name:

  Homo sapiens BAR/IMD domain containing adaptor protein 2 (BAIAP2), transcript variant 3, mRNA.

• Gene ID:

  10458

• UniProt:

  Q9UQB8

• Conjugation:

  Unconjugated

• Related Pathways:

  Adherens junction, Regulation of actin cytoskeleton

• Field of Research:

  Adherens junction, Regulation of actin cytoskeleton

• Dilution:

  WB 1:2000, IHC 1:150, IF 1:100

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Function:

  Druggable Genome

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  BAIAP2

• Overview:

  Carrier-free (BSA/glycerol-free) BAIAP2 mouse monoclonal antibody, clone LBI8G8

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=10458

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9UQB8