PDE1B Mouse Monoclonal Antibody [Clone ID: LBI6E4]

• Background:

  Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1B, are calmodulin (see MIM 114180) -dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 [PubMed 1326532]) . [supplied by OMIM]

• Synonyms:

  PDE1B1; PDES1B

• Gene Name:

  Homo sapiens phosphodiesterase 1B (PDE1B), transcript variant 1, mRNA.

• Gene ID:

  5153

• UniProt:

  Q01064

• Conjugation:

  Unconjugated

• Related Pathways:

  Calcium signaling pathway, Progesterone-mediated oocyte maturation, Purine metabolism

• Field of Research:

  Calcium signaling pathway, Progesterone-mediated oocyte maturation, Purine metabolism

• Dilution:

  WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Function:

  Druggable Genome

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  PDE1B

• Overview:

  Carrier-free (BSA/glycerol-free) PDE1B mouse monoclonal antibody, clone LBI6E4

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=5153

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q01064