AP2M1 Mouse Monoclonal Antibody [Clone ID: LBI1F10]

• Background:

  This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

• Synonyms:

  AP50; CLAPM1; mu2

• Gene Name:

  Homo sapiens adaptor related protein complex 2 subunit mu 1 (AP2M1), transcript variant 2, mRNA.

• Gene ID:

  1173

• UniProt:

  Q96CW1

• Conjugation:

  Unconjugated

• Related Pathways:

  Endocytosis, Huntington's disease

• Field of Research:

  Endocytosis, Huntington's disease

• Dilution:

  WB 1:2000, IF 1:100, FLOW 1:100

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Function:

  Druggable Genome

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  AP2M1

• Overview:

  Carrier-free (BSA/glycerol-free) AP2M1 mouse monoclonal antibody, clone LBI1F10

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=1173

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q96CW1