CDK2 Mouse Monoclonal Antibody [Clone ID: LBI4D3]

• Background:

  The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B) . Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. [provided by RefSeq]

• Synonyms:

  CDKN2; p33 (CDK2)

• Gene Name:

  Homo sapiens cyclin dependent kinase 2 (CDK2), transcript variant 1, mRNA.

• Gene ID:

  1017

• UniProt:

  P24941

• Conjugation:

  Unconjugated

• Related Pathways:

  Cell cycle, Oocyte meiosis, p53 signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Small cell lung cancer

• Field of Research:

  Cell cycle, Oocyte meiosis, p53 signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Small cell lung cancer

• Dilution:

  WB 1:2000, IF 1:100, FLOW 1:100

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Function:

  Druggable Genome, Protein Kinase

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  CDK2

• Overview:

  Carrier-free (BSA/glycerol-free) CDK2 mouse monoclonal antibody, clone LBI4D3

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=1017

• Uniprot URL:

  https://www.uniprot.org/uniprot/P24941