Cytoplasmic dynein 1 light intermediate chain 1 (DYNC1LI1) Mouse Monoclonal Antibody [Clone ID: LBI1C5]

• Background:

  Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress throuh the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores.

• Synonyms:

  DLC-A; DNCLI1; LIC1

• Gene Name:

  Homo sapiens dynein cytoplasmic 1 light intermediate chain 1 (DYNC1LI1), transcript variant 1, mRNA.

• Gene ID:

  51143

• UniProt:

  Q9Y6G9

• Conjugation:

  Unconjugated

• Dilution:

  WB 1:2000, IF 1:100, FLOW 1:100

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  DYNC1LI1

• Overview:

  Carrier-free (BSA/glycerol-free) DYNC1LI1 mouse monoclonal antibody, clone LBI1C5

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=51143

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9Y6G9