ATP5F1B Mouse Monoclonal Antibody [Clone ID: LBI4E5]

• Background:

  This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c) . This gene encodes the beta subunit of the catalytic core.

• Synonyms:

  ATPMB; ATPSB; HEL-S-271

• Gene Name:

  Homo sapiens ATP synthase F1 subunit beta (ATP5F1B), mRNA; nuclear gene for mitochondrial product.

• Gene ID:

  506

• UniProt:

  P06576

• Conjugation:

  Unconjugated

• Related Pathways:

  Alzheimer's disease, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease

• Field of Research:

  Alzheimer's disease, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease

• Dilution:

  WB 1:1000, IF 1:100, Flow 1:100

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Function:

  Druggable Genome

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  ATP5F1B

• Overview:

  Carrier-free (BSA/glycerol-free) ATP5B mouse monoclonal antibody, clone LBI4E5

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=506

• Uniprot URL:

  https://www.uniprot.org/uniprot/P06576