GRF2 (RAPGEF1) Mouse Monoclonal Antibody [Clone ID: UMLBI140]

• Background:

  This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]

• Synonyms:

  C3G; GRF2

• Gene Name:

  Homo sapiens Rap guanine nucleotide exchange factor 1 (RAPGEF1), transcript variant 2, mRNA.

• Gene ID:

  2889

• UniProt:

  Q13905

• Conjugation:

  Unconjugated

• Related Pathways:

  Focal adhesion, Insulin signaling pathway, Neurotrophin signaling pathway, Renal cell carcinoma

• Field of Research:

  Focal adhesion, Insulin signaling pathway, Neurotrophin signaling pathway, Renal cell carcinoma

• Dilution:

  IHC 1:100~200

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Function:

  Druggable Genome

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  RAPGEF1

• Overview:

  Carrier-free (BSA/glycerol-free) RAPGEF1 mouse monoclonal antibody, clone UMLBI140

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=2889

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q13905