RNF14 Mouse Monoclonal Antibody [Clone ID: LBI3A4]

• Background:

  The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Six alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq, Jan 2011]

• Synonyms:

  ARA54; HFB30; HRIHFB2038; TRIAD2

• Gene Name:

  Homo sapiens ring finger protein 14 (RNF14), transcript variant 4, mRNA.

• Gene ID:

  9604

• UniProt:

  Q9UBS8

• Conjugation:

  Unconjugated

• Dilution:

  WB 1:200

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Function:

  Druggable Genome, Transcription Factors

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  RNF14

• Overview:

  Carrier-free (BSA/glycerol-free) RNF14 mouse monoclonal antibody, clone LBI3A4

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=9604

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9UBS8