RUNX3 Mouse Monoclonal Antibody [Clone ID: LBI2G1]

• Background:

  This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Synonyms:

  AML2; CBFA3; PEBP2aC

• Gene Name:

  Homo sapiens RUNX family transcription factor 3 (RUNX3), transcript variant 1, mRNA.

• Gene ID:

  864

• UniProt:

  Q13761

• Conjugation:

  Unconjugated

• Dilution:

  WB 1:2000, IHC 1:500

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Function:

  Transcription Factors

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  RUNX3

• Overview:

  Carrier-free (BSA/glycerol-free) RUNX3 mouse monoclonal antibody, clone LBI2G1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=864

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q13761