C Fos (FOS) Mouse Monoclonal Antibody [Clone ID: LBI4H1]

• Background:

  The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq, Jul 2008]

• Synonyms:

  AP-1; C-FOS; p55

• Gene Name:

  Homo sapiens Fos proto-oncogene, AP-1 transcription factor subunit (FOS), mRNA.

• Gene ID:

  2353

• UniProt:

  P01100

• Conjugation:

  Unconjugated

• Related Pathways:

  B cell receptor signaling pathway, Colorectal cancer, MAPK signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Toll-like receptor signaling pathway

• Field of Research:

  B cell receptor signaling pathway, Colorectal cancer, MAPK signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Toll-like receptor signaling pathway

• Dilution:

  WB 1:2000

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Function:

  Druggable Genome, Transcription Factors

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  FOS

• Overview:

  Carrier-free (BSA/glycerol-free) FOS mouse monoclonal antibody, clone LBI4H1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=2353

• Uniprot URL:

  https://www.uniprot.org/uniprot/P01100