MMP7 Mouse Monoclonal Antibody [Clone ID: LBI3G7]

• Background:

  Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]

• Synonyms:

  MMP-7; MPSL1; PUMP-1

• Gene Name:

  Homo sapiens matrix metallopeptidase 7 (MMP7), mRNA.

• Gene ID:

  4316

• UniProt:

  P09237

• Conjugation:

  Unconjugated

• Related Pathways:

  Wnt signaling pathway

• Field of Research:

  Wnt signaling pathway

• Dilution:

  IHC 1:150

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Function:

  Druggable Genome, Protease

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  MMP7

• Overview:

  Carrier-free (glycerol/BSA-free) MMP7 mouse monoclonal antibody, clone LBI3G7

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=4316

• Uniprot URL:

  https://www.uniprot.org/uniprot/P09237