NIPP1 (PPP1R8) Mouse Monoclonal Antibody [Clone ID: LBI4E5]

• Background:

  This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. [provided by RefSeq, Jul

• Synonyms:

  ARD-1; ARD1; NIPP-1; NIPP1; PRO2047

• Gene Name:

  Homo sapiens protein phosphatase 1 regulatory subunit 8 (PPP1R8), transcript variant 2, mRNA.

• Gene ID:

  5511

• UniProt:

  Q12972

• Conjugation:

  Unconjugated

• Dilution:

  WB 1:2000, IHC 1:150

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Function:

  Druggable Genome, Transcription Factors

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  PPP1R8

• Overview:

  Carrier-free (BSA/glycerol-free) PPP1R8 mouse monoclonal antibody, clone LBI4E5

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=5511

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q12972