TNFRSF4 Mouse Monoclonal Antibody [Clone ID: UMLBI276]

• Background:

  The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008]

• Synonyms:

  ACT35; CD134; IMD16; OX40; TXGP1L

• Gene Name:

  Homo sapiens TNF receptor superfamily member 4 (TNFRSF4), mRNA.

• Gene ID:

  7293

• UniProt:

  P43489

• Conjugation:

  Unconjugated

• Related Pathways:

  Cytokine-cytokine receptor interaction

• Field of Research:

  Cytokine-cytokine receptor interaction

• Concentration:

  0.5~1.0 mg/ml (Lot Dependent)

• Dilution:

  IHC 1:100~300

• Form:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Buffer:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Function:

  Transmembrane

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  TNFRSF4

• Overview:

  OX40 (TNFRSF4) mouse monoclonal antibody, clone UMLBI276

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=7293

• Uniprot URL:

  https://www.uniprot.org/uniprot/P43489