MSH2 Mouse Monoclonal Antibody [Clone ID: UMLBI259]

• Background:

  This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC) . When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

• Synonyms:

  COCA1; FCC1; hMSH2; HNPCC; HNPCC1; LCFS2; MMRCS2

• Gene Name:

  Homo sapiens mutS homolog 2 (MSH2), transcript variant 1, mRNA.

• Gene ID:

  4436

• UniProt:

  P43246

• Conjugation:

  Unconjugated

• Related Pathways:

  Colorectal cancer, Mismatch repair, Pathways in cancer

• Field of Research:

  Colorectal cancer, Mismatch repair, Pathways in cancer

• Concentration:

  0.5~1.0 mg/ml (Lot Dependent)

• Dilution:

  IHC 1:2400

• Form:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Buffer:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Function:

  Druggable Genome, Stem cell - Pluripotency

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  MSH2

• Overview:

  MSH2 mouse monoclonal antibody, clone UMLBI259

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=4436

• Uniprot URL:

  https://www.uniprot.org/uniprot/P43246