Proteasome subunit alpha type 6 (PSMA6) Mouse Monoclonal Antibody [Clone ID: UMLBI102]

• Background:

  The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome. [provided by RefSeq, Jul 2008]

• Synonyms:

  IOTA; p27K; PROS27

• Gene Name:

  Homo sapiens proteasome 20S subunit alpha 6 (PSMA6), transcript variant 1, mRNA.

• Gene ID:

  5687

• UniProt:

  P60900

• Conjugation:

  Unconjugated

• Related Pathways:

  Proteasome

• Field of Research:

  Proteasome

• Concentration:

  0.5~1.0 mg/ml (Lot Dependent)

• Dilution:

  IHC 1:100, IF 1:100

• Form:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Buffer:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Function:

  Druggable Genome, Protease, Stem cell - Pluripotency

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  PSMA6

• Overview:

  PSMA6 mouse monoclonal antibody, clone UMLBI102

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=5687

• Uniprot URL:

  https://www.uniprot.org/uniprot/P60900