Cytokeratin 8 (KRT8) Mouse Monoclonal Antibody [Clone ID: UMLBI1]

• Background:

  Keratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.

• Synonyms:

  CARD2; CK-8; CK8; CYK8; K2C8; K8; KO

• Gene Name:

  Homo sapiens keratin 8 (KRT8), transcript variant 2, mRNA.

• Gene ID:

  3856

• UniProt:

  P05787

• Conjugation:

  Unconjugated

• Concentration:

  0.5~1.0 mg/ml (Lot Dependent)

• Dilution:

  WB 1:500~1000, IHC 1:50, IF 1:50~100

• Form:

  PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Buffer:

  PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Function:

  Druggable Genome

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  KRT8

• Overview:

  KRT8/CK8 mouse monoclonal antibody, clone UMLBI1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=3856

• Uniprot URL:

  https://www.uniprot.org/uniprot/P05787