SAE1 Mouse Monoclonal Antibody [Clone ID: LBI2B2]

• Background:

  Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]) . [supplied by OMIM, Mar 2010]

• Synonyms:

  AOS1; HSPC140; SUA1; UBLE1A

• Gene Name:

  SUMO1 activating enzyme subunit 1

• Gene ID:

  10055

• UniProt:

  Q9UBE0

• Conjugation:

  Unconjugated

• Related Pathways:

  Ubiquitin mediated proteolysis

• Field of Research:

  Ubiquitin mediated proteolysis

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:2000

• Form:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Buffer:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  SAE1

• Overview:

  SAE1 mouse monoclonal antibody, clone LBI2B2

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=10055

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9UBE0