XRCC3 Mouse Monoclonal Antibody [Clone ID: LBI4C8]

• Background:

  This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]

• Synonyms:

  CMM6

• Gene Name:

  X-ray repair complementing defective repair in Chinese hamster cells 3

• Gene ID:

  7517

• UniProt:

  O43542

• Conjugation:

  Unconjugated

• Related Pathways:

  Homologous recombination

• Field of Research:

  Homologous recombination

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:2000

• Form:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Buffer:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Function:

  Druggable Genome

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  XRCC3

• Overview:

  XRCC3 mouse monoclonal antibody, clone LBI4C8

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=7517

• Uniprot URL:

  https://www.uniprot.org/uniprot/O43542