LATS2 Mouse Monoclonal Antibody [Clone ID: LBI2D3]

• Background:

  This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. [provided by RefSeq, Jul 2008]

• Synonyms:

  KPM

• Gene Name:

  Large tumor suppressor kinase 2

• Gene ID:

  26524

• UniProt:

  Q9NRM7

• Conjugation:

  Unconjugated

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:2000

• Form:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Buffer:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Function:

  Druggable Genome, Protein Kinase

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  LATS2

• Overview:

  LATS2 mouse monoclonal antibody, clone LBI2D3

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=26524

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9NRM7