Fibrinogen gamma chain (FGG) Mouse Monoclonal Antibody [Clone ID: LBI5C9]

• Background:

  The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul

• Synonyms:

  Fibrinogen; fibrinogen gamma chain; gamma chain; gamma polypeptide

• Gene Name:

  Fibrinogen gamma chain

• Gene ID:

  2266

• UniProt:

  P02679

• Conjugation:

  Unconjugated

• Related Pathways:

  Complement and coagulation cascades

• Field of Research:

  Complement and coagulation cascades

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:400~4000, IHC 1:150

• Form:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Buffer:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Function:

  Druggable Genome, Secreted Protein, Transmembrane

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  FGG

• Overview:

  FGG mouse monoclonal antibody, clone LBI5C9

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=2266

• Uniprot URL:

  https://www.uniprot.org/uniprot/P02679