PFKP Mouse Monoclonal Antibody [Clone ID: LBI1D6]

• Background:

  The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11) . PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM; MIM 610681) and liver (PFKL; MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2. [supplied by OMIM]

• Synonyms:

  ATP-PFK; PFK-C; PFK-P; PFKF

• Gene Name:

  Phosphofructokinase, platelet

• Gene ID:

  5214

• UniProt:

  Q01813

• Conjugation:

  Unconjugated

• Related Pathways:

  Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Pentose phosphate pathway

• Field of Research:

  Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Metabolic pathways, Pentose phosphate pathway

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100

• Form:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Buffer:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Function:

  Druggable Genome

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  PFKP

• Overview:

  PFKP mouse monoclonal antibody, clone LBI1D6

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=5214

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q01813