PEX5 Mouse Monoclonal Antibody [Clone ID: LBI6G8]

• Background:

  The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD) . Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]

• Synonyms:

  PBD2A; PBD2B; PTS1-BP; PTS1R; PXR1; RCDP5

• Gene Name:

  Peroxisomal biogenesis factor 5

• Gene ID:

  5830

• UniProt:

  P50542

• Conjugation:

  Unconjugated

• Concentration:

  0.87 mg/ml

• Dilution:

  WB 1:2000, IF 1:100

• Form:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Buffer:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Function:

  Druggable Genome

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  PEX5

• Overview:

  PEX5 mouse monoclonal antibody, clone LBI6G8

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=5830

• Uniprot URL:

  https://www.uniprot.org/uniprot/P50542