ElF2 alpha (EIF2S1) Mouse Monoclonal Antibody [Clone ID: LBI1B10]

• Background:

  The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161) . The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]) . [supplied by OMIM]

• Synonyms:

  EIF-2; EIF-2A; EIF-2alpha; EIF2; EIF2A

• Gene Name:

  Eukaryotic translation initiation factor 2 subunit alpha

• Gene ID:

  1965

• UniProt:

  P05198

• Conjugation:

  Unconjugated

• Concentration:

  0.58 mg/ml

• Dilution:

  WB 1:1000~2000, IHC 1:50

• Form:

  PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Buffer:

  PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  EIF2S1

• Overview:

  Anti-EIF2S1 mouse monoclonal antibody, clone LBI1B10

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=1965

• Uniprot URL:

  https://www.uniprot.org/uniprot/P05198